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segment polarity gene : ウィキペディア英語版 | segment polarity gene A segmentation gene is a generic term for a gene whose function is to specify tissue pattern in each repeated unit of a segmented organism. Animals are constructed of segments; however, Drosophila segments also contain subdivided compartments. In embryonic drosophila, these segments are called parasegments. Parasegments distinguish them from adult segments, which has 14 segments.〔http://cuttlefish.bio.indiana.edu:7082/allied-data/lk/interactive-fly/segment/engrail1.htm〕 In the fruit fly ''Drosophila melanogaster'', segment polarity genes help to define the anterior and posterior polarities within each embryonic parasegment by regulating the transmission of signals via the Wnt signaling pathway and Hedgehog signaling pathway. Segment polarity genes are expressed in the embryo following expression of the gap genes and pair-rule genes. The most commonly cited examples of these genes are ''engrailed'' and ''gooseberry'' in ''D. melanogaster''. The segment polarity is the last step in embryonic development and a repeated pattern where each half of each segment is deleted and a mirror-image is duplicated and reversed to replace that half segment; thus, forming a pattern element.〔Perrimon, N., & Mahowald, A. P. (1987). Multiple functions of segment polarity genes in Drosophila. Developmental biology, 119(2), 587-600.〕 ==Segment polarity in Drosophila== Segmentation polarity occurs during the release of morphogens, which functions to differentiate patterns within sections.〔http://cuttlefish.bio.indiana.edu:7082/allied-data/lk/interactive-fly/aignfam/sgmtplty.htm#dafka〕 The pattern that develop depends on gradients of these morphogens.〔http://cuttlefish.bio.indiana.edu:7082/allied-data/lk/interactive-fly/aignfam/sgmtplty.htm#dafka〕
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